Cp*Rh<sup>III</sup>/Chiral Disulfonate/CuOAc Catalyst System for the Enantioselective Intramolecular Oxyamination of Alkenes
نویسندگان
چکیده
The enantioselective intramolecular oxyamination of unsaturated alkoxyamines using a hybrid catalytic system consisting Cp*RhIII/chiral disulfonate/CuOAc is described. Tetrahydrofuran derivatives with tetrasubstituted chiral center were obtained under the optimized conditions in 91:9–97:3 er. use sterically hindered disulfonate and Cu additive was essential for high enantioselectivity.
منابع مشابه
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چکیده ندارد.
Enantioselective intramolecular hydroarylation of alkenes via directed C-H bond activation.
Highly enantioselective catalytic intramolecular ortho-alkylation of aromatic imines containing alkenyl groups tethered at the meta position relative to the imine directing group has been achieved using [RhCl(coe)2]2 and chiral phosphoramidite ligands. Cyclization of substrates containing 1,1- and 1,2-disubstituted as well as trisubstituted alkenes were achieved with enantioselectivities >90% e...
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ژورنال
عنوان ژورنال: ACS Catalysis
سال: 2021
ISSN: ['2155-5435']
DOI: https://doi.org/10.1021/acscatal.1c04699